Review



th17 cell marker  (R&D Systems)


Bioz Verified Symbol R&D Systems is a verified supplier
Bioz Manufacturer Symbol R&D Systems manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 94
      Buy from Supplier

    Structured Review

    R&D Systems th17 cell marker
    Patients with steatohepatitis show T lymphocytes infiltration in meninges. Representative images of sections stained using an antibody against an specific marker for T lymphocytes (CD4) are shown in ( A ) for patients with different grades of liver disease (bar 100 μm). Representative images of sections stained with Tfh and <t>Th17</t> subtype markers are shown in ( B and C ), respectively for a control subject and a patient with SH2 (bar 50 μm). D shows a double immunofluorescence (CD4 in red and CX3CR1 in green) showing a SH2 patient with infiltration of CD4 + CD28 − T lymphocytes in meninges (bar 25 μm). E shows a representative image stained with anti-CD20, a marker of B lymphocytes, in a section of the same SH2 patient shown in A for T lymphocytes. F shows a representative image of a control patient stained with anti-CD20. The number of CD4 + , Tfh, Th17 and CD4 + CD28 − T lymphocytes was quantified in patients with different grades of liver disease ( G ). One-way ANOVA with Bonferroni post-hoc test was performed to compare all groups. Values are the mean ± SEM of 4–9 individuals per group. Values significantly different from controls are indicated by asterisks, from SH1 patients by a and from SH2 patients by b. *p < 0.05; ***p < 0.005; a p < 0.05; aaa p < 0.005; b p < 0.05; bbb p < 0.005.
    Th17 Cell Marker, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/th17 cell marker/product/R&D Systems
    Average 94 stars, based on 7 article reviews
    th17 cell marker - by Bioz Stars, 2026-05
    94/100 stars

    Images

    1) Product Images from "The Cerebellum of Patients with Steatohepatitis Shows Lymphocyte Infiltration, Microglial Activation and Loss of Purkinje and Granular Neurons"

    Article Title: The Cerebellum of Patients with Steatohepatitis Shows Lymphocyte Infiltration, Microglial Activation and Loss of Purkinje and Granular Neurons

    Journal: Scientific Reports

    doi: 10.1038/s41598-018-21399-6

    Patients with steatohepatitis show T lymphocytes infiltration in meninges. Representative images of sections stained using an antibody against an specific marker for T lymphocytes (CD4) are shown in ( A ) for patients with different grades of liver disease (bar 100 μm). Representative images of sections stained with Tfh and Th17 subtype markers are shown in ( B and C ), respectively for a control subject and a patient with SH2 (bar 50 μm). D shows a double immunofluorescence (CD4 in red and CX3CR1 in green) showing a SH2 patient with infiltration of CD4 + CD28 − T lymphocytes in meninges (bar 25 μm). E shows a representative image stained with anti-CD20, a marker of B lymphocytes, in a section of the same SH2 patient shown in A for T lymphocytes. F shows a representative image of a control patient stained with anti-CD20. The number of CD4 + , Tfh, Th17 and CD4 + CD28 − T lymphocytes was quantified in patients with different grades of liver disease ( G ). One-way ANOVA with Bonferroni post-hoc test was performed to compare all groups. Values are the mean ± SEM of 4–9 individuals per group. Values significantly different from controls are indicated by asterisks, from SH1 patients by a and from SH2 patients by b. *p < 0.05; ***p < 0.005; a p < 0.05; aaa p < 0.005; b p < 0.05; bbb p < 0.005.
    Figure Legend Snippet: Patients with steatohepatitis show T lymphocytes infiltration in meninges. Representative images of sections stained using an antibody against an specific marker for T lymphocytes (CD4) are shown in ( A ) for patients with different grades of liver disease (bar 100 μm). Representative images of sections stained with Tfh and Th17 subtype markers are shown in ( B and C ), respectively for a control subject and a patient with SH2 (bar 50 μm). D shows a double immunofluorescence (CD4 in red and CX3CR1 in green) showing a SH2 patient with infiltration of CD4 + CD28 − T lymphocytes in meninges (bar 25 μm). E shows a representative image stained with anti-CD20, a marker of B lymphocytes, in a section of the same SH2 patient shown in A for T lymphocytes. F shows a representative image of a control patient stained with anti-CD20. The number of CD4 + , Tfh, Th17 and CD4 + CD28 − T lymphocytes was quantified in patients with different grades of liver disease ( G ). One-way ANOVA with Bonferroni post-hoc test was performed to compare all groups. Values are the mean ± SEM of 4–9 individuals per group. Values significantly different from controls are indicated by asterisks, from SH1 patients by a and from SH2 patients by b. *p < 0.05; ***p < 0.005; a p < 0.05; aaa p < 0.005; b p < 0.05; bbb p < 0.005.

    Techniques Used: Staining, Marker, Control, Immunofluorescence

    Scheme summarizing the analysis performed and their localization in cerebellum. Histo-architectural analysis was performed on post-mortem human cerebellum sections. Neuronal density analysis (black X) was performed in Purkinje layer (blue circles) and in granular layer (light blue spotted layer). Microglial (brown cloud, Iba1) and astroglial (brown star, GFAP) activation analysis was performed in molecular layer (in orange) and white matter (white). Infiltration of B lymphocytes (green circle, CD20) and of total T lymphocytes (yellow square, CD4) and the T lymphocytes subtypes Tfh, Th17 and CD4 + CD28 − was analyzed in meninges (in red).
    Figure Legend Snippet: Scheme summarizing the analysis performed and their localization in cerebellum. Histo-architectural analysis was performed on post-mortem human cerebellum sections. Neuronal density analysis (black X) was performed in Purkinje layer (blue circles) and in granular layer (light blue spotted layer). Microglial (brown cloud, Iba1) and astroglial (brown star, GFAP) activation analysis was performed in molecular layer (in orange) and white matter (white). Infiltration of B lymphocytes (green circle, CD20) and of total T lymphocytes (yellow square, CD4) and the T lymphocytes subtypes Tfh, Th17 and CD4 + CD28 − was analyzed in meninges (in red).

    Techniques Used: Activation Assay



    Similar Products

    th17 cell marker rorgt  (Santa Cruz Biotechnology)
    90
    Santa Cruz Biotechnology th17 cell marker rorgt
    Th17 Cell Marker Rorgt, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/th17 cell marker rorgt/product/Santa Cruz Biotechnology
    Average 90 stars, based on 1 article reviews
    th17 cell marker rorgt - by Bioz Stars, 2026-05
    90/100 stars
    		  Buy from Supplier
    th17 cell marker  (R&D Systems)
    94
    R&D Systems th17 cell marker
    Patients with steatohepatitis show T lymphocytes infiltration in meninges. Representative images of sections stained using an antibody against an specific marker for T lymphocytes (CD4) are shown in ( A ) for patients with different grades of liver disease (bar 100 μm). Representative images of sections stained with Tfh and <t>Th17</t> subtype markers are shown in ( B and C ), respectively for a control subject and a patient with SH2 (bar 50 μm). D shows a double immunofluorescence (CD4 in red and CX3CR1 in green) showing a SH2 patient with infiltration of CD4 + CD28 − T lymphocytes in meninges (bar 25 μm). E shows a representative image stained with anti-CD20, a marker of B lymphocytes, in a section of the same SH2 patient shown in A for T lymphocytes. F shows a representative image of a control patient stained with anti-CD20. The number of CD4 + , Tfh, Th17 and CD4 + CD28 − T lymphocytes was quantified in patients with different grades of liver disease ( G ). One-way ANOVA with Bonferroni post-hoc test was performed to compare all groups. Values are the mean ± SEM of 4–9 individuals per group. Values significantly different from controls are indicated by asterisks, from SH1 patients by a and from SH2 patients by b. *p < 0.05; ***p < 0.005; a p < 0.05; aaa p < 0.005; b p < 0.05; bbb p < 0.005.
    Th17 Cell Marker, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/th17 cell marker/product/R&D Systems
    Average 94 stars, based on 1 article reviews
    th17 cell marker - by Bioz Stars, 2026-05
    94/100 stars
    		  Buy from Supplier

    Image Search Results


    Patients with steatohepatitis show T lymphocytes infiltration in meninges. Representative images of sections stained using an antibody against an specific marker for T lymphocytes (CD4) are shown in ( A ) for patients with different grades of liver disease (bar 100 μm). Representative images of sections stained with Tfh and Th17 subtype markers are shown in ( B and C ), respectively for a control subject and a patient with SH2 (bar 50 μm). D shows a double immunofluorescence (CD4 in red and CX3CR1 in green) showing a SH2 patient with infiltration of CD4 + CD28 − T lymphocytes in meninges (bar 25 μm). E shows a representative image stained with anti-CD20, a marker of B lymphocytes, in a section of the same SH2 patient shown in A for T lymphocytes. F shows a representative image of a control patient stained with anti-CD20. The number of CD4 + , Tfh, Th17 and CD4 + CD28 − T lymphocytes was quantified in patients with different grades of liver disease ( G ). One-way ANOVA with Bonferroni post-hoc test was performed to compare all groups. Values are the mean ± SEM of 4–9 individuals per group. Values significantly different from controls are indicated by asterisks, from SH1 patients by a and from SH2 patients by b. *p < 0.05; ***p < 0.005; a p < 0.05; aaa p < 0.005; b p < 0.05; bbb p < 0.005.

    Journal: Scientific Reports

    Article Title: The Cerebellum of Patients with Steatohepatitis Shows Lymphocyte Infiltration, Microglial Activation and Loss of Purkinje and Granular Neurons

    doi: 10.1038/s41598-018-21399-6

    Figure Lengend Snippet: Patients with steatohepatitis show T lymphocytes infiltration in meninges. Representative images of sections stained using an antibody against an specific marker for T lymphocytes (CD4) are shown in ( A ) for patients with different grades of liver disease (bar 100 μm). Representative images of sections stained with Tfh and Th17 subtype markers are shown in ( B and C ), respectively for a control subject and a patient with SH2 (bar 50 μm). D shows a double immunofluorescence (CD4 in red and CX3CR1 in green) showing a SH2 patient with infiltration of CD4 + CD28 − T lymphocytes in meninges (bar 25 μm). E shows a representative image stained with anti-CD20, a marker of B lymphocytes, in a section of the same SH2 patient shown in A for T lymphocytes. F shows a representative image of a control patient stained with anti-CD20. The number of CD4 + , Tfh, Th17 and CD4 + CD28 − T lymphocytes was quantified in patients with different grades of liver disease ( G ). One-way ANOVA with Bonferroni post-hoc test was performed to compare all groups. Values are the mean ± SEM of 4–9 individuals per group. Values significantly different from controls are indicated by asterisks, from SH1 patients by a and from SH2 patients by b. *p < 0.05; ***p < 0.005; a p < 0.05; aaa p < 0.005; b p < 0.05; bbb p < 0.005.

    Article Snippet: The primary antibodies used were: anti-Iba1 as microglial marker (Wako, 019-19741; 1:300 for 30 min), anti-GFAP as astrocyte marker (DAKO, IR524; ready to use for 20 min), anti CD4 for T lymphocyte staining (DAKO, M7310, 1:50 for 20 min), anti CD20 for B lymphocyte detection (DAKO, IR604, ready to use for 20 min), anti PD1 (Abcam, ab52587, 1:100 for 30 min) as Tfh cell marker and anti CCR6 as Th17 cell marker (R&D System, MAB195, 1:150 for 30 min).

    Techniques: Staining, Marker, Control, Immunofluorescence

    Scheme summarizing the analysis performed and their localization in cerebellum. Histo-architectural analysis was performed on post-mortem human cerebellum sections. Neuronal density analysis (black X) was performed in Purkinje layer (blue circles) and in granular layer (light blue spotted layer). Microglial (brown cloud, Iba1) and astroglial (brown star, GFAP) activation analysis was performed in molecular layer (in orange) and white matter (white). Infiltration of B lymphocytes (green circle, CD20) and of total T lymphocytes (yellow square, CD4) and the T lymphocytes subtypes Tfh, Th17 and CD4 + CD28 − was analyzed in meninges (in red).

    Journal: Scientific Reports

    Article Title: The Cerebellum of Patients with Steatohepatitis Shows Lymphocyte Infiltration, Microglial Activation and Loss of Purkinje and Granular Neurons

    doi: 10.1038/s41598-018-21399-6

    Figure Lengend Snippet: Scheme summarizing the analysis performed and their localization in cerebellum. Histo-architectural analysis was performed on post-mortem human cerebellum sections. Neuronal density analysis (black X) was performed in Purkinje layer (blue circles) and in granular layer (light blue spotted layer). Microglial (brown cloud, Iba1) and astroglial (brown star, GFAP) activation analysis was performed in molecular layer (in orange) and white matter (white). Infiltration of B lymphocytes (green circle, CD20) and of total T lymphocytes (yellow square, CD4) and the T lymphocytes subtypes Tfh, Th17 and CD4 + CD28 − was analyzed in meninges (in red).

    Article Snippet: The primary antibodies used were: anti-Iba1 as microglial marker (Wako, 019-19741; 1:300 for 30 min), anti-GFAP as astrocyte marker (DAKO, IR524; ready to use for 20 min), anti CD4 for T lymphocyte staining (DAKO, M7310, 1:50 for 20 min), anti CD20 for B lymphocyte detection (DAKO, IR604, ready to use for 20 min), anti PD1 (Abcam, ab52587, 1:100 for 30 min) as Tfh cell marker and anti CCR6 as Th17 cell marker (R&D System, MAB195, 1:150 for 30 min).

    Techniques: Activation Assay